head to head
Neither is simply harder - they are hard in different places. Agatha Christie: Hercule Poirot - The London Case demands more variance; Portal 2 demands more optimization.

Optimization · Pure Optimization
A detective adventure about gathering clues to solve an authored murder case.

Optimization · Pure Optimization
A first-person puzzle game where seeing the solution is the whole skill.
Agatha Christie: Hercule Poirot - The London Case leans Optimization (Pure Optimization); Portal 2 leans Optimization (Pure Optimization).
Portal 2 leans clearly harder on execution.
Agatha Christie: Hercule Poirot - The London Case
Point-and-click interaction needs no physical skill
Portal 2
Portal placement requires some precision but timing is lenient.
Agatha Christie: Hercule Poirot - The London Case leans a little harder on reads, though the gap is small.
Agatha Christie: Hercule Poirot - The London Case
Suspects are scripted, not adapting to your deductions
Portal 2
No opponent; puzzles are static.
Agatha Christie: Hercule Poirot - The London Case leans clearly harder on variance.
Agatha Christie: Hercule Poirot - The London Case
Clues hidden until found, but fully authored
Portal 2
Puzzles are deterministic with no randomness.
Portal 2 leans clearly harder on optimization.
Agatha Christie: Hercule Poirot - The London Case
Connecting evidence to solve the fixed case is the work
Portal 2
Solving the puzzle's logic IS the entire game.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.