head to head
Neither is simply harder - they are hard in different places. Alchemy Mysteries: Prague Legends demands more variance; Portal demands more execution.

Optimization · Pure Optimization
A hidden-object adventure about solving a fixed chain of puzzles and clues.

Optimization · Pure Optimization
The portal-gun puzzle game whose solutions are everything.
Alchemy Mysteries: Prague Legends leans Optimization (Pure Optimization); Portal leans Optimization (Pure Optimization).
Portal leans clearly harder on execution.
Alchemy Mysteries: Prague Legends
Point-and-click hidden-object hunting needs no twitch skill
Portal
Portal placement timing modest.
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Alchemy Mysteries: Prague Legends
Solo - no adaptive opponent
Portal
No adversary modeling player.
Alchemy Mysteries: Prague Legends leans clearly harder on variance.
Alchemy Mysteries: Prague Legends
Object and clue locations hidden until found, then fixed
Portal
Deterministic chambers; no randomness.
Portal leans a little harder on optimization, though the gap is small.
Alchemy Mysteries: Prague Legends
Solving the scripted puzzle and item chain drives progress
Portal
Pure puzzle-solving optimization.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.