head to head
Neither is simply harder - they are hard in different places. Borderlands 2 demands more execution; Ring of Pain demands more variance.

Optimization · Systems & Chaos
Loot-shooter RPG built on gear chasing.

Variance · Systems & Chaos
A card dungeon crawler where the random circular ring layout creates high-variance positioning puzzles to optimize around.
Borderlands 2 leans Optimization (Systems & Chaos); Ring of Pain leans Variance (Systems & Chaos).
Borderlands 2 leans clearly harder on execution.
Borderlands 2
Aim matters but generous hit feel
Ring of Pain
Clicking room cards has no manual dexterity requirement
Borderlands 2 leans a little harder on reads, though the gap is small.
Borderlands 2
Enemies are scripted loot fodder
Ring of Pain
Enemies use fixed behaviors; no adaptive play
Ring of Pain leans clearly harder on variance.
Borderlands 2
Procedurally generated weapon drops vary
Ring of Pain
Ring layout randomness creates very high run-to-run unpredictability
Borderlands 2 leans a little harder on optimization, though the gap is small.
Borderlands 2
Skill trees and gear math heavily solved
Ring of Pain
Gear and stat synergies reward analytical item evaluation
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.