head to head
Neither is simply harder - they are hard in different places. Borderlands 2 demands more execution; Teamfight Tactics demands more reads.

Optimization · Systems & Chaos
Loot-shooter RPG built on gear chasing.

Optimization · Systems & Chaos
An autobattler decided by economy curves and shop variance management.
Borderlands 2 leans Optimization (Systems & Chaos); Teamfight Tactics leans Optimization (Systems & Chaos).
Borderlands 2 leans clearly harder on execution.
Borderlands 2
Aim matters but generous hit feel
Teamfight Tactics
No mechanical inputs of note
Teamfight Tactics leans clearly harder on reads.
Borderlands 2
Enemies are scripted loot fodder
Teamfight Tactics
Scout opponents but no live adaptation
Teamfight Tactics leans a little harder on variance, though the gap is small.
Borderlands 2
Procedurally generated weapon drops vary
Teamfight Tactics
Shop rolls and augment offerings swing lobbies
Teamfight Tactics leans a little harder on optimization, though the gap is small.
Borderlands 2
Skill trees and gear math heavily solved
Teamfight Tactics
Econ curves, positioning, and comps are near-solved
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.