head to head
Neither is simply harder - they are hard in different places. Cities: Skylines II demands more variance; Portal demands more execution.

Optimization · Pure Optimization
Sandbox city-builder where everything bends to optimization.

Optimization · Pure Optimization
The portal-gun puzzle game whose solutions are everything.
Cities: Skylines II leans Optimization (Pure Optimization); Portal leans Optimization (Pure Optimization).
Portal leans clearly harder on execution.
Cities: Skylines II
no mechanical demand
Portal
Portal placement timing modest.
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Cities: Skylines II
no adversary
Portal
No adversary modeling player.
Cities: Skylines II leans clearly harder on variance.
Cities: Skylines II
minor sim noise
Portal
Deterministic chambers; no randomness.
Cities: Skylines II leans a little harder on optimization, though the gap is small.
Cities: Skylines II
traffic, zoning, budgets solvable
Portal
Pure puzzle-solving optimization.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.