head to head
Cities: SkylinesvsOthello
Cities: Skylines leans Optimization (Pure Optimization); Othello leans Optimization (Pure Optimization).
Cities: SkylinesOthello
Axis by axis
Execution0 vs 0
Even - both lean on execution about the same.
Reads0 vs 2
Othello leans harder on reads: Perfect information leaves little room for psychological play
Variance1 vs 0
Cities: Skylines leans harder on variance: Minor disaster events if enabled.
Optimization10 vs 9
Cities: Skylines leans harder on optimization: Traffic flow, zoning, and budgets are fully solvable.
Two games can score the same on an axis and still test it in very different ways - read each rationale, not just the number.

