head to head
Neither is simply harder - they are hard in different places. Clair Obscur: Expedition 33 demands more optimization; Grand Theft Auto V demands more reads.

Optimization · Practiced Mastery
Turn-based RPG whose reactive parry timing layers execution onto build optimization.

Execution · Practiced Mastery
Sandbox crime playground spanning shooting, driving, and a persistent online economy.
Clair Obscur: Expedition 33 leans Optimization (Practiced Mastery); Grand Theft Auto V leans Execution (Practiced Mastery).
Clair Obscur: Expedition 33 leans a little harder on execution, though the gap is small.
Clair Obscur: Expedition 33
Parry and dodge timing inside turn-based combat
Grand Theft Auto V
Driving and shooting demand decent inputs.
Grand Theft Auto V leans clearly harder on reads.
Clair Obscur: Expedition 33
Bosses follow learnable scripted patterns
Grand Theft Auto V
Online PvP exists but mostly gear/positioning, not modeling.
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Clair Obscur: Expedition 33
Some unknown attack strings on first encounter
Grand Theft Auto V
Some mission and lobby randomness.
Clair Obscur: Expedition 33 leans clearly harder on optimization.
Clair Obscur: Expedition 33
Pictos, builds, and turn economy are solvable
Grand Theft Auto V
Heists, money loops, builds learnable.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.