head to head
Neither is harder. They score identically on all four axes, so the difference between them is in kind, not degree.

Execution · Pure Mechanics
Comic-panel beat 'em up notorious for punishing health drain and tough fights.

Execution · Pure Mechanics
Light-gun reflex shooting that converges to memorized spawn choreography.
Comix Zone leans Execution (Pure Mechanics); Time Crisis 4 leans Execution (Pure Mechanics).
Same score on execution - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Brutal one-life brawling demands clean play
Time Crisis 4
Snap aim and cover-pedal timing decide every section
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Enemies follow fixed attack scripts
Time Crisis 4
Enemy waves are fully scripted set-pieces
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Everything is placed and scripted
Time Crisis 4
Spawns are fixed after one credit
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Panel routes and item use are memorizable
Time Crisis 4
Memorizing spawn order is how scores climb
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.