head to head
Neither is simply harder - they are hard in different places. Grand Theft Auto: San Andreas demands more optimization; Lost Planet: Extreme Condition demands more execution.

Optimization · Practiced Mastery
A sprawling open-world crime epic with RPG-style character stats across a whole state.

Execution · Practiced Mastery
Frozen-planet shooter about managing heat while gunning down giant bugs.
Grand Theft Auto: San Andreas leans Optimization (Practiced Mastery); Lost Planet: Extreme Condition leans Execution (Practiced Mastery).
Lost Planet: Extreme Condition leans clearly harder on execution.
Grand Theft Auto: San Andreas
Flying school and drive-bys need decent hands
Lost Planet: Extreme Condition
Grapple movement and Akrid weak-point shooting
Lost Planet: Extreme Condition leans clearly harder on reads.
Grand Theft Auto: San Andreas
Gang AI is scripted, never adaptive
Lost Planet: Extreme Condition
Multiplayer modes add some mind games
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Grand Theft Auto: San Andreas
Territory wars and traffic add light randomness
Lost Planet: Extreme Condition
Campaign encounters are fixed
Grand Theft Auto: San Andreas leans clearly harder on optimization.
Grand Theft Auto: San Andreas
Stats, gym, weapon skill, and routes reward systematic play
Lost Planet: Extreme Condition
Thermal energy management and boss weak points
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.