head to head
Slay the Spire asks more than Loop Hero, and the gap is variance.

Optimization · Pure Optimization
An auto-battling deckbuilder about building a loop to defeat the Lich.

Optimization · Systems & Chaos
A deckbuilding roguelike where adapting builds to random offers wins runs.
Loop Hero leans Optimization (Pure Optimization); Slay the Spire leans Optimization (Systems & Chaos).
Loop Hero leans a little harder on execution, though the gap is small.
Loop Hero
Autobattler, almost no inputs.
Slay the Spire
Turn-based, zero input precision required.
Slay the Spire leans a little harder on reads, though the gap is small.
Loop Hero
Enemies follow scripts.
Slay the Spire
Enemy intents shown; behaviour scripted, not adaptive.
Slay the Spire leans clearly harder on variance.
Loop Hero
Card draws and loot drops randomize.
Slay the Spire
Card and relic offers drive every run.
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Loop Hero
Deck and tile placement reward deep optimization.
Slay the Spire
Deck shaping and combat math are solvable.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.