head to head
Neither is simply harder - they are hard in different places. Metroid II: Return of Samus demands more variance; Portal 2 demands more optimization.

Optimization · Pure Optimization
The Game Boy expedition that turns Metroid into a methodical extermination checklist deep inside SR388.

Optimization · Pure Optimization
A first-person puzzle game where seeing the solution is the whole skill.
Metroid II: Return of Samus leans Optimization (Pure Optimization); Portal 2 leans Optimization (Pure Optimization).
Metroid II: Return of Samus leans a little harder on execution, though the gap is small.
Metroid II: Return of Samus
Cramped Game Boy combat against Metroid forms.
Portal 2
Portal placement requires some precision but timing is lenient.
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Metroid II: Return of Samus
Creatures follow fixed behaviours.
Portal 2
No opponent; puzzles are static.
Metroid II: Return of Samus leans clearly harder on variance.
Metroid II: Return of Samus
Disorienting unknown caverns until mapped.
Portal 2
Puzzles are deterministic with no randomness.
Portal 2 leans clearly harder on optimization.
Metroid II: Return of Samus
Hunting all 39 Metroids is methodical route work.
Portal 2
Solving the puzzle's logic IS the entire game.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.