head to head
Neither is simply harder - they are hard in different places. Myst demands more variance; Portal demands more execution.

Optimization · Pure Optimization
Landmark first-person puzzle adventure solved by careful observation and note-taking.

Optimization · Pure Optimization
The portal-gun puzzle game whose solutions are everything.
Myst leans Optimization (Pure Optimization); Portal leans Optimization (Pure Optimization).
Portal leans clearly harder on execution.
Myst
Clicking through static scenes
Portal
Portal placement timing modest.
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Myst
No adversary at all
Portal
No adversary modeling player.
Myst leans clearly harder on variance.
Myst
Clues hidden until found, then fixed forever
Portal
Deterministic chambers; no randomness.
Portal leans a little harder on optimization, though the gap is small.
Myst
Observation-driven logic puzzles with deterministic solutions
Portal
Pure puzzle-solving optimization.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.