head to head
Neither is simply harder - they are hard in different places. Persona 3 Reload demands more variance; Portal 2 demands more execution.

Optimization · Pure Optimization
A turn-based JRPG won by persona fusion and social-link routing.

Optimization · Pure Optimization
A first-person puzzle game where seeing the solution is the whole skill.
Persona 3 Reload leans Optimization (Pure Optimization); Portal 2 leans Optimization (Pure Optimization).
Portal 2 leans clearly harder on execution.
Persona 3 Reload
Turn-based, low input demand
Portal 2
Portal placement requires some precision but timing is lenient.
Persona 3 Reload leans a little harder on reads, though the gap is small.
Persona 3 Reload
Scripted enemies and bosses
Portal 2
No opponent; puzzles are static.
Persona 3 Reload leans clearly harder on variance.
Persona 3 Reload
Weakness, crit, and fusion rolls
Portal 2
Puzzles are deterministic with no randomness.
Portal 2 leans a little harder on optimization, though the gap is small.
Persona 3 Reload
Persona fusion and social link routing central
Portal 2
Solving the puzzle's logic IS the entire game.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.