head to head
vs
The Binding of Isaac: Afterbirth+vsThe First Descendant
The Binding of Isaac: Afterbirth+ leans Execution (Twitch Chaos); The First Descendant leans Optimization (Practiced Mastery).
The Binding of Isaac: Afterbirth+The First Descendant
Axis by axis
Execution7 vs 6
The Binding of Isaac: Afterbirth+ leans harder on execution: Dodging bullet patterns while aiming tears is constant
Reads0 vs 1
The First Descendant leans harder on reads: PvE co-op throughout with no meaningful adaptive opponent
Variance7 vs 6
The Binding of Isaac: Afterbirth+ leans harder on variance: Item pools, room layouts and pickups define each run
Optimization7 vs 8
The First Descendant leans harder on optimization: Module builds and Descendant loadouts are extensively theory-crafted
Two games can score the same on an axis and still test it in very different ways - read each rationale, not just the number.