head to head
Neither is meaningfully harder - they pose close to the same test. The widest gap is execution, and it is a single point.

Execution · Practiced Mastery
Big Daddy POV return to Rapture with tighter combat systems.

Execution · Practiced Mastery
A stylish anime bullet-hell shooter about cleaning up poison.
BioShock 2 leans Execution (Practiced Mastery); Poison Control leans Execution (Practiced Mastery).
Poison Control leans a little harder on execution, though the gap is small.
BioShock 2
Dual-wield drill and gun timing matter.
Poison Control
Bullet-hell dodging and aiming precision
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
BioShock 2
Splicer AI scripted, not adaptive.
Poison Control
Fixed boss patterns, no adaptation
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
BioShock 2
Sister-gathering waves add randomness.
Poison Control
Some enemy spawn randomness
BioShock 2 leans a little harder on optimization, though the gap is small.
BioShock 2
Plasmid combos and gear loadouts solvable.
Poison Control
Build/route optimization secondary
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.