head to head
Neither is harder. They score identically on all four axes, so the difference between them is in kind, not degree.

Optimization · Pure Optimization
Tactical grid combat plus studio management, both solvable with planning.

Optimization · Pure Optimization
Strategy sim about evolving a pathogen to outpace the world's cure effort.
Chroma Squad leans Optimization (Pure Optimization); Plague Inc. leans Optimization (Pure Optimization).
Same score on execution - which means the number cannot separate them. The difference is in what each one asks of you.
Chroma Squad
Turn-based commands, no dexterity involved
Plague Inc.
Tapping menus only
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Chroma Squad
Enemy AI follows simple mappable rules
Plague Inc.
World response is algorithmic, not adaptive to you
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Chroma Squad
Hit rolls and episode events add modest noise
Plague Inc.
Spread events and cure pace fluctuate
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Chroma Squad
Studio economy, crafting and teamwork combos are the puzzle
Plague Inc.
Evolution-point timing strategies are largely solved
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.