head to head
Neither is harder. They score identically on all four axes, so the difference between them is in kind, not degree.

Execution · Pure Mechanics
Comic-panel beat 'em up notorious for punishing health drain and tough fights.

Execution · Pure Mechanics
Rail-shooter execution and memorised form-switching through fixed aerial set pieces.
Comix Zone leans Execution (Pure Mechanics); Panzer Dragoon Orta leans Execution (Pure Mechanics).
Same score on execution - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Brutal one-life brawling demands clean play
Panzer Dragoon Orta
Lock-on aiming, dodging and form-switching under fire define it
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Enemies follow fixed attack scripts
Panzer Dragoon Orta
Enemy waves are scripted rail set pieces
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Everything is placed and scripted
Panzer Dragoon Orta
Routes and spawns barely change
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Comix Zone
Panel routes and item use are memorizable
Panzer Dragoon Orta
Form choice per encounter and pattern memory perfect scores
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.