head to head
Neither is harder. They score identically on all four axes, so the difference between them is in kind, not degree.

Execution · Practiced Mastery
The black-sheep sequel whose passive enemies and dominant guns sand the series' skill ceiling way down.

Execution · Practiced Mastery
Superhero sequel adding melee combat and a karma-split power arsenal in New Marais.
Devil May Cry 2 leans Execution (Practiced Mastery); inFamous 2 leans Execution (Practiced Mastery).
Same score on execution - which means the number cannot separate them. The difference is in what each one asks of you.
Devil May Cry 2
Infamously easy; guns trivialize most encounters
inFamous 2
Faster combat with melee and aimed powers
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Devil May Cry 2
Passive enemy AI never pressures, let alone adapts
inFamous 2
Scripted enemy factions, no adaptation
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Devil May Cry 2
Flat authored levels hide little
inFamous 2
Static world, fixed encounters
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Devil May Cry 2
Amulet builds and boss patterns fall fast
inFamous 2
Karma-gated power trees shape the run
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.