head to head
Dr. Mario Online Rx asks more than Dr. Mario, and the gap is reads.

Execution · Practiced Mastery
Rapid capsule placement against a clock, with planning for chains under random pill draws.

Execution · Pure Mechanics
A falling-capsule puzzle testing speed placement to clear virus layouts.
Dr. Mario leans Execution (Practiced Mastery); Dr. Mario Online Rx leans Execution (Pure Mechanics).
Dr. Mario Online Rx leans a little harder on execution, though the gap is small.
Dr. Mario
Fast capsule placement under rising speed decides clears
Dr. Mario Online Rx
Fast capsule placement under speed-up is the lead skill
Dr. Mario Online Rx leans clearly harder on reads.
Dr. Mario
Versus mode exists but garbage exchange rewards speed, not prediction
Dr. Mario Online Rx
Versus play adds light anticipation of opponent tempo
Dr. Mario Online Rx leans a little harder on variance, though the gap is small.
Dr. Mario
Random pill colors against fixed virus layouts, quickly bounded
Dr. Mario Online Rx
Capsule colors are random but quickly mappable
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Dr. Mario
Chain setups and virus-clearing order follow known patterns
Dr. Mario Online Rx
Clearing virus layouts has known efficient patterns
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.