head to head
Neither is simply harder - they are hard in different places. Galactic Civilizations II: Dread Lords demands more variance; Portal 2 demands more execution.

Optimization · Pure Optimization
Space 4X where out-planning the galaxy's economy wins wars before they start.

Optimization · Pure Optimization
A first-person puzzle game where seeing the solution is the whole skill.
Galactic Civilizations II: Dread Lords leans Optimization (Pure Optimization); Portal 2 leans Optimization (Pure Optimization).
Portal 2 leans clearly harder on execution.
Galactic Civilizations II: Dread Lords
Turn-based; zero dexterity
Portal 2
Portal placement requires some precision but timing is lenient.
Galactic Civilizations II: Dread Lords leans a little harder on reads, though the gap is small.
Galactic Civilizations II: Dread Lords
Acclaimed AI still follows mappable doctrines
Portal 2
No opponent; puzzles are static.
Galactic Civilizations II: Dread Lords leans clearly harder on variance.
Galactic Civilizations II: Dread Lords
Galaxy generation and unexplored starts
Portal 2
Puzzles are deterministic with no randomness.
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Galactic Civilizations II: Dread Lords
Economy sliders, ship design, and expansion math dominate
Portal 2
Solving the puzzle's logic IS the entire game.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.