head to head
Neither is simply harder - they are hard in different places. Inscryption demands more variance; Portal 2 demands more execution.

Optimization · Pure Optimization
A meta deckbuilder where engine-building beats the scripted opponent.

Optimization · Pure Optimization
A first-person puzzle game where seeing the solution is the whole skill.
Inscryption leans Optimization (Pure Optimization); Portal 2 leans Optimization (Pure Optimization).
Portal 2 leans clearly harder on execution.
Inscryption
No reflex demands; turn-based card play.
Portal 2
Portal placement requires some precision but timing is lenient.
Inscryption leans clearly harder on reads.
Inscryption
Scripted opponents with light bluff moments, not true adaptation.
Portal 2
No opponent; puzzles are static.
Inscryption leans clearly harder on variance.
Inscryption
Card draws and event choices randomized.
Portal 2
Puzzles are deterministic with no randomness.
Portal 2 leans a little harder on optimization, though the gap is small.
Inscryption
Deck construction and sacrifice math drive victories.
Portal 2
Solving the puzzle's logic IS the entire game.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.