head to head
Neither is simply harder - they are hard in different places. ISS Pro Evolution 2 demands more reads; Super Mario Odyssey demands more optimization.

Execution · Pure Mechanics
Classic football execution - touch, timing and finishing - with human mind-games on top.

Execution · Pure Mechanics
A 3D platformer whose joy lives in tight movement and capture-driven traversal.
ISS Pro Evolution 2 leans Execution (Pure Mechanics); Super Mario Odyssey leans Execution (Pure Mechanics).
Super Mario Odyssey leans a little harder on execution, though the gap is small.
ISS Pro Evolution 2
First-touch control, through-ball timing and finishing decide matches
Super Mario Odyssey
Precise platforming and capture-move tech ceiling.
ISS Pro Evolution 2 leans clearly harder on reads.
ISS Pro Evolution 2
Versus humans, baiting tackles and disguising passes matters
Super Mario Odyssey
No adaptive opponents whatsoever.
ISS Pro Evolution 2 leans a little harder on variance, though the gap is small.
ISS Pro Evolution 2
Slight bounce and keeper randomness within a deterministic sim
Super Mario Odyssey
Almost no randomness in level design.
Super Mario Odyssey leans clearly harder on optimization.
ISS Pro Evolution 2
Formation and player-role knowledge gives a modest edge
Super Mario Odyssey
Moon routes and movement tech learnable.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.