head to head
Neither is simply harder - they are hard in different places. Portal 2 demands more execution; Vampire Survivors demands more variance.

Optimization · Pure Optimization
A first-person puzzle game where seeing the solution is the whole skill.

Optimization · Pure Optimization
An auto-attacker where picking the right weapon evolutions wins by itself.
Portal 2 leans Optimization (Pure Optimization); Vampire Survivors leans Optimization (Pure Optimization).
Portal 2 leans clearly harder on execution.
Portal 2
Portal placement requires some precision but timing is lenient.
Vampire Survivors
Movement is trivial; no aim or precision required.
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Portal 2
No opponent; puzzles are static.
Vampire Survivors
Enemies follow fixed spawn scripts; no adaptive opponent.
Vampire Survivors leans clearly harder on variance.
Portal 2
Puzzles are deterministic with no randomness.
Vampire Survivors
Level-up offerings and pickup drops are randomized.
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Portal 2
Solving the puzzle's logic IS the entire game.
Vampire Survivors
Evolution paths and weapon combinations fully solve the run.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.