head to head
Neither is meaningfully harder - they pose close to the same test. The widest gap is execution, and it is a single point.

Execution · Twitch Chaos
An open-world survival shooter set in a hostile irradiated Zone full of anomalies and scarce supplies.

Execution · Twitch Chaos
Twin-stick roguelike where a crying child fights basement horrors with random unholy upgrades.
S.T.A.L.K.E.R. 2: Heart of Chornobyl leans Execution (Twitch Chaos); The Binding of Isaac leans Execution (Twitch Chaos).
The Binding of Isaac leans a little harder on execution, though the gap is small.
S.T.A.L.K.E.R. 2: Heart of Chornobyl
Lethal gunfights with recoil, bleed, and ballistics punish sloppy aim
The Binding of Isaac
Twin-stick dodging through bullet-dense rooms
S.T.A.L.K.E.R. 2: Heart of Chornobyl leans a little harder on reads, though the gap is small.
S.T.A.L.K.E.R. 2: Heart of Chornobyl
A-Life NPCs roam but never model the player adaptively
The Binding of Isaac
Enemies follow fixed or random patterns
The Binding of Isaac leans a little harder on variance, though the gap is small.
S.T.A.L.K.E.R. 2: Heart of Chornobyl
Anomalies, emissions, stash rolls, and unknown Zone layouts hide information
The Binding of Isaac
Item and room RNG defines every run
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
S.T.A.L.K.E.R. 2: Heart of Chornobyl
Artifact hunting, gear upkeep economy, and routing through the Zone
The Binding of Isaac
Item synergy knowledge converts luck into wins
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.