head to head
Neither is simply harder - they are hard in different places. Escape Doodland demands more variance; Super Mario Odyssey demands more optimization.

Execution · Pure Mechanics
A reflex runner-platformer of fleeing a monster through hazard-filled levels.

Execution · Pure Mechanics
A 3D platformer whose joy lives in tight movement and capture-driven traversal.
Escape Doodland leans Execution (Pure Mechanics); Super Mario Odyssey leans Execution (Pure Mechanics).
Same score on execution - which means the number cannot separate them. The difference is in what each one asks of you.
Escape Doodland
Reflex timing while fleeing a monster is the core
Super Mario Odyssey
Precise platforming and capture-move tech ceiling.
Escape Doodland leans a little harder on reads, though the gap is small.
Escape Doodland
Monster chase is scripted, not adaptive
Super Mario Odyssey
No adaptive opponents whatsoever.
Escape Doodland leans clearly harder on variance.
Escape Doodland
Obstacle layouts add some randomness
Super Mario Odyssey
Almost no randomness in level design.
Super Mario Odyssey leans clearly harder on optimization.
Escape Doodland
Learning level hazards improves survival slightly
Super Mario Odyssey
Moon routes and movement tech learnable.
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.