head to head
Neither is harder. They score identically on all four axes, so the difference between them is in kind, not degree.

Optimization · Pure Optimization
A classic psychological adventure where an amnesiac navigates surreal delusions to recover his identity.

Optimization · Pure Optimization
Methodically decoding intricate fixed mechanisms hidden in a puzzle dollhouse.
Sanitarium leans Optimization (Pure Optimization); The Room 4: Old Sins leans Optimization (Pure Optimization).
Same score on execution - which means the number cannot separate them. The difference is in what each one asks of you.
Sanitarium
Point-and-click navigation requires no dexterity
The Room 4: Old Sins
Twisting mechanisms onscreen takes no dexterity
Same score on reads - which means the number cannot separate them. The difference is in what each one asks of you.
Sanitarium
No opponents; the delusions follow a fixed narrative
The Room 4: Old Sins
A fixed dollhouse of secrets; nothing adapts
Same score on variance - which means the number cannot separate them. The difference is in what each one asks of you.
Sanitarium
Surreal puzzle logic is unknown until reasoned out
The Room 4: Old Sins
Mechanisms are hidden information until discovered
Same score on optimization - which means the number cannot separate them. The difference is in what each one asks of you.
Sanitarium
Every chapter is a deterministic puzzle to solve
The Room 4: Old Sins
Each puzzle box is a deterministic mechanism to decode
A matching score does not mean a matching test. Two games can both sit at 10 on execution and demand completely different things of you - which is why the reasoning above matters more than the number beside it.